Warm ischemia time, postreperfusion syndrome and initial poor function after liver transplantation: are they connected?
نویسندگان
چکیده
منابع مشابه
Postreperfusion syndrome during liver transplantation
As surgical and graft preservation techniques have improved and immunosuppressive drugs have advanced, liver transplantation (LT) is now considered the gold standard for treating patients with end-stage liver disease worldwide. However, despite the improved survival following LT, severe hemodynamic disturbances during LT remain a serious issue for the anesthesiologist. The greatest hemodynamic ...
متن کاملInitial Poor Graft Dysfunction and Primary Graft Non-Function After Orthotopic Liver Transplantation
Orthotopic liver transplantation (OLT) has become the effective treatment for end-stage liver diseases. Since the 1980s, the successful rate of liver transplantation has increased with the improvement of operative methods and the use of University of Wisconsin (UW) solution. Nevertheless, liver procurement and implantation are inevitably associated with allograft damage. Lack of donor liver hin...
متن کاملInfluencing Factor Analysis on Initial Poor Graft Function after Liver Transplantation
To analyze the related influencing factors for initial poor graft function (IPGF) after liver transplantation (LT). 107 cases underwent liver transplantation from March in 2014 to November in 2015 were selected randomly. The group of IPGF is confirmed if ALT and/or AST are above 1500IU/L, while non-IPGF below 1500IU/L within 72h after LT. The donor related influencing factors includes age, sour...
متن کاملWarm ischemia time-dependent variation in liver damage, inflammation, and function in hepatic ischemia/reperfusion injury.
BACKGROUND Hepatic ischemia/reperfusion (I/R) injury is characterized by hepatocellular damage, sterile inflammation, and compromised postoperative liver function. Generally used mouse I/R models are too severe and poorly reflect the clinical injury profile. The aim was to establish a mouse I/R model with better translatability using hepatocellular injury, liver function, and innate immune para...
متن کاملAssociation Between Flushed Fluid Potassium Concentration and Severe Postreperfusion Syndrome in Deceased Donor Liver Transplantation
BACKGROUND Predicting the occurrence of severe postreperfusion syndrome (PRS) is clinically challenging. We investigated whether the flushed fluid potassium concentration (FFK) was associated with severe PRS in deceased donor liver transplantation (DDLT). MATERIAL AND METHODS Forty adult DDLT recipients were enrolled in this retrospective study. Effluent solution samples were collected at the e...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2015
ISSN: 1364-8535
DOI: 10.1186/cc14458